Unbiased Stereology

Unbiased Stereology

Author: Vyvyan Howard

Publisher: Taylor & Francis

ISBN:

Page: 246

View: 277

In Unbiased Stereology, the authors present a practical guide to making unbiased 3D measurements using microscopy. Stereology is the statistical inference of geometric parameters from spatially sampled information; it is considered unbiased when the test probes are positioned in an appropriately random manner. Now that unbiased stereology is required for nerve-cell counts in neurotoxicology by the FDA and by many journals before the acceptance of an article or study, this book is essential reading. It includes only those stereological techniques that have been tried and tested by actual application. Specific topics covered include: random sampling and random geometry; the estimation of feature volume, surface, length, number and mean particle size; as well as statistics for stereologists.

Unbiased Stereology

Those new to bioscience research as well as experienced practitioners will find that Mouton’s explanations are the perfect companion for stereology courses and workshops.

Unbiased Stereology

Author: Peter R. Mouton

Publisher: JHU Press

ISBN: 1421402289

Page: 200

View: 278

This update to Peter R. Mouton’s pioneering work provides bioscientists with the concepts needed in order to apply the principles and practices of unbiased stereology to research involving biological tissues. Mouton starts with a brief explanation of the history and theory of the process before defining the terms, concepts, and tools of unbiased stereological procedures. He compares and contrasts the procedures with less-exacting approaches to quantitative analysis of biological structure using specific examples from biomedical literature. The book incorporates existing best practices with new methodologies, such as the Rare Event Protocol, while simplifying the dense, often difficult literature on the subject to show the utility and importance of unbiased stereology. This clear, insightful guide goes a step further than other books on this subject by demonstrating not only how to use unbiased stereology but also how to interpret and present the results. Written by the official U.S. representative to the International Society for Stereology, this is the most complete, up-to-date resource on the science of unbiased stereology. Those new to bioscience research as well as experienced practitioners will find that Mouton’s explanations are the perfect companion for stereology courses and workshops.

Unbiased Stereology

Now that unbiased stereology is required for nerve-cell counts in neurotoxicology by the FDA and by many journals before the acceptance of an article or study, this book is essential reading.

Unbiased Stereology

Author: Vyvyan Howard

Publisher: Springer

ISBN: 9789813083448

Page: 246

View: 591

In Unbiased Stereology, the authors present a practical guide to making unbiased 3D measurements using microscopy. Stereology is the statistical inference of geometric parameters from spatially sampled information; it is considered unbiased when the test probes are positioned in an appropriately random manner. Now that unbiased stereology is required for nerve-cell counts in neurotoxicology by the FDA and by many journals before the acceptance of an article or study, this book is essential reading. It includes only those stereological techniques that have been tried and tested by actual application. Specific topics covered include: random sampling and random geometry; the estimation of feature volume, surface, length, number and mean particle size; as well as statistics for stereologists.

Neurostereology

Focusing on the most important uses of stereology, this book will be a powerful resource for the international community of neuroscience researchers in academic institutions, government agencies, and the pharmaceutical industry.

Neurostereology

Author: P. R. Mouton

Publisher: John Wiley & Sons

ISBN: 1118444183

Page: 280

View: 698

Stereological methods provide researchers with unparalleled quantitative data from tissue samples and allow for well-evidenced research advances in a broad range of scientific fields. Presenting a concise introduction to the methodology and application of stereological research in neuroscience, Neurostereology provides a fuller understanding of the use of these methods in research and a means for replicating successful scientific approaches. Providing sound footing for future research, Neurostereology is a useful tool for basic and clinical researchers and advanced students looking to integrate these methods into their research.

Pain

Stereology of arbitrary particles : a review of unbiased number and size
estimators and the presentation of some new ones , in memory of William R .
Thompson . J Microsc 1986 ; 143 : 3 – 45 . Howard CV , Reed MG . Unbiased
stereology ...

Pain

Author:

Publisher:

ISBN:

Page:

View: 626

Medical Imaging 2004

K. A. Dorph-Peterson, H. J. G. Gundersen and E. B. V. Jensen, "Non-uniform
systematic sampling in stereology", J. of ... M. G. Reed, "Unbiased stereology -
three-dimensional measurement in microscopy", New York, N.Y. Springer, 1998.

Medical Imaging 2004

Author:

Publisher:

ISBN:

Page: 2158

View: 725

Thermal and Moisture Transport in Fibrous Materials

Mouton P R ( 2002 ) , Principles and Practices of Unbiased Stereology : An
Introduction for Bioscientists , Baltimore , Johns Hopkins University Press .
Mouton P R , Gokhale A M , Ward N L and West M J ( 2002a ) , “ Stereological
length ...

Thermal and Moisture Transport in Fibrous Materials

Author: N Pan

Publisher: Woodhead Publishing

ISBN: 9781845690571

Page: 632

View: 667

The transfer of heat and moisture through textiles is vital to the manufacture and design of clothing, technical and protective textiles. Continued advances in textile processing technology, the growth of manufactured nonwovens and the application of nanotechnology have resulted in a wealth of research in order to characterise the behaviour of these materials. Thermal and moisture transport in fibrous materials provides a comprehensive guide of the technological developments and scientific understanding in this area. The first section summarises the structure, geometry and stereology of fibrous materials. The fundamentals of wetting and its dynamics are also discussed. Part two analyses thermal and liquid interactions in textiles and offers insights into the thermodynamic behaviour of moisture as well as heat and moisture coupling. The book concludes with chapters on the human thermoregulatory system, interfacing between fibrous materials and the human body and innovative computer modelling simulations. Thermal and moisture transport in fibrous materials is an essential reference for all those involved in the textile industry, especially those concerned with the design and manufacture of technical textiles and protective clothing. Summarises the structure, geometry and stereology of fibrous materials Discusses the fundamentals of wetting and its dynamics Analyses thermal and liquid interactions in textiles

APMIS

The application of related to nuclear size and size variability ( 33 ) , stereology to
cancer research was already disand , similarly , quantitative parallels are
available cussed by Weibel in 1972 ( 45 ) ... These emphasis on unbiased
stereology .

APMIS

Author:

Publisher:

ISBN:

Page:

View: 749

Experimental Biology and Medicine

1. Howard CV. Reed MG. Unbiased Stereology. ... Stereological analysis of
anisotropic structures using directional statistics. Appl Statist ... A stereological
method for estimating length density of the arterial vascular system. Am J Physiol
266: ...

Experimental Biology and Medicine

Author:

Publisher:

ISBN:

Page:

View: 758

Electron Microscopy

Major aims are now to explore cell structure and dynamics through rapid freezing
and electron tomography , to obtain quantitative information about normal and
pathological cells from unbiased stereology , and to expand knowledge about ...

Electron Microscopy

Author:

Publisher:

ISBN:

Page:

View: 814

Advances in Applied Probability

Unbiased stereological estimation of the surface area of gradient surface
processes . ... Workshop Stereology , Stochastic Geometry ( Aarhus , October
1983 ) , eds E . B . Jensen and H . J . G . Gundersen , Institute of Mathematics
Aarhus ...

Advances in Applied Probability

Author:

Publisher:

ISBN:

Page:

View: 471

Handbook of Clinical Automation Robotics and Optimization

Definitions Stereology , a word coined by Hans Elias in 1963,51 is a set of simple
and efficient rules , used in the ... skin , exhibit a degree of layered organization
and orientation ( anisotropy ) , making unbiased stereological sampling difficult .

Handbook of Clinical Automation  Robotics  and Optimization

Author: Gerald J. Kost

Publisher: Wiley-Interscience

ISBN:

Page: 952

View: 176

This comprehensive landmark book describes the technology of the future in diagnostic medicine, how to integrate it into the modern hospital and how to work with people to adapt, change and plan for a smooth transition to a fully robotic laboratory. Features an extensive section on point-of-care testing along with a modern perspective of how this will transform medicine. Global experts in their fields have authored all chapters which include a unique one on machine vision and another (with several plates) that discusses the automation of a clinical laboratory in Japan.

Selected Papers on Optical Microscopy

M. Reed and V. Howard , Unbiased Stereology : Three - Dimensional
Measurements in Microscopy , The Royal Microscopic Society ( Great Britain ) ,
Oxford University Press , 1998. Although stereology is not a new method in
optical ...

Selected Papers on Optical Microscopy

Author: Marion B. Rhodes

Publisher: Society of Photo Optical

ISBN:

Page: 602

View: 261

SPIE Milestones are collections of seminal papers from the world literature covering important discoveries and developments in optics and photonics.

The Journal of Neuroscience

The volume of medial septum was measured by unbiased stereology with optical
disector ; n = number of animals . Figure 1. Basal forebrain cholinergic neurons in
p75 NTR -. NTR p751 NTR NTR p75 NTR ( Butcher , 1995 ) in mice carrying a ...

The Journal of Neuroscience

Author:

Publisher:

ISBN:

Page:

View: 341