The Molecular Switch

The Molecular Switch articulates a biophysical perspective on signaling, showing how allostery—a powerful explanation of how molecules function across all biological domains—can be reformulated using equilibrium statistical mechanics, ...

The Molecular Switch

Author: Rob Phillips

Publisher: Princeton University Press

ISBN: 0691200246

Page: 440

View: 877

A signature feature of living organisms is their ability to carry out purposeful actions by taking stock of the world around them. To that end, cells have an arsenal of signaling molecules linked together in signaling pathways, which switch between inactive and active conformations. The Molecular Switch articulates a biophysical perspective on signaling, showing how allostery—a powerful explanation of how molecules function across all biological domains—can be reformulated using equilibrium statistical mechanics, applied to diverse biological systems exhibiting switching behaviors, and successfully unify seemingly unrelated phenomena. Rob Phillips weaves together allostery and statistical mechanics via a series of biological vignettes, each of which showcases an important biological question and accompanying physical analysis. Beginning with the study of ligand-gated ion channels and their role in problems ranging from muscle action to vision, Phillips then undertakes increasingly sophisticated case studies, from bacterial chemotaxis and quorum sensing to hemoglobin and its role in mammalian physiology. He looks at G-protein coupled receptors as well as the role of allosteric molecules in gene regulation. Phillips concludes by surveying problems in biological fidelity and offering a speculative chapter on the relationship between allostery and biological Maxwell demons. Appropriate for graduate students and researchers in biophysics, physics, engineering, biology, and neuroscience, The Molecular Switch presents a unified, quantitative model for describing biological signaling phenomena.

Molecular Switches

Providing principles and applications this book brings you everything you need to know about molecular switches - a hot topic in the nanoworld.

Molecular Switches

Author: Ben L. Feringa

Publisher: John Wiley & Sons

ISBN: 352763441X

Page: 824

View: 998

The long-awaited second edition of the successful book covering molecular switches now in two volumes! Providing principles and applications this book brings you everything you need to know about molecular switches - a hot topic in the nanoworld. The major classes of molecular switches including catenanes, rotaxanes, azobenzenes together with polymer and biomolecular switching systems and DNA based switches are covered. Chemists and material scientists interested in one of the most innovative areas of their science will benefit greatly from reading this book. "This book will appeal most to organic chemists, because of the way new structures are introduced through their synthesis, but it will also provide a useful introduction for other scientists, provided they are conversant with molecular structures." (Organic and Biomolecular Chemistry) "... a comprehensive and up-to-date insight ..." (Chemistry & Industry)

Molecular and Supramolecular Information Processing

Perfectly complements Biomolecular Information Processing, also by Prof. Katz, and available as a two-volume set. Edited by a renowned and much cited chemist, this book covers the whole span of molecular computers.

Molecular and Supramolecular Information Processing

Author: Evgeny Katz

Publisher: John Wiley & Sons

ISBN: 3527645454

Page: 382

View: 152

Edited by a renowned and much cited chemist, this book covers the whole span of molecular computers that are based on non-biological systems. The contributions by all the major scientists in the field provide an excellent overview of the latest developments in this rapidly expanding area. A must-have for all researchers working on this very hot topic. Perfectly complements Biomolecular Information Processing, also by Prof. Katz, and available as a two-volume set.

Nanostructures Based on Molecular Materials

The objective of the action is to investigate fundamental factors of importance for
the functionality of organic chemical molecules capable of switching , and also
the construction of extreme miniaturized sensors . " " A molecular switch is
defined ...

Nanostructures Based on Molecular Materials

Author: W. Göpel

Publisher: Vch Pub

ISBN:

Page: 377

View: 684

Molecular Nanowires and Other Quantum Objects

Single - Molecule Switches The molecular switch is a highly non - trivial element
of molecular electronics . Switching implies bistability ( or even multiple stability )
of the molecule . The latter can be realized via bistability of electronic structure ...

Molecular Nanowires and Other Quantum Objects

Author: A. S. Alexandrov

Publisher: Springer

ISBN:

Page: 428

View: 817

Proceedings of the NATO Advanced Research Workshop, Bled, Slovenia from 7 to 9 September 2003

Human Gene Therapy

Mary Ann Liebert , Inc. TAXI / UAS : A Molecular Switch to Control Expression of
Genes In Vivo JACQUES P. DELORT ... in mammals by the application of a
molecular switch that would allow physicians and / or investigators to turn
individual ...

Human Gene Therapy

Author:

Publisher:

ISBN:

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View: 139

Recent Advances and Issues in Molecular Nanotechnology

The system behaves as a one - time - only switch . The UCLA scientists
recognized that their rotaxane system was only the first step in the development
of a more useful molecular switch . A year later , they reported on a redesigned
switch that ...

Recent Advances and Issues in Molecular Nanotechnology

Author: David E. Newton

Publisher: Greenwood

ISBN:

Page: 306

View: 493

This book covers an exciting new field involving the manipulation of individual atoms and molecules to produce materials and devices with very precise, predictable properties.

Molecular Wires and Nanoscale Conductors

For the molecular switch tunnel junction environment , we evaluated the
temperature dependent switching amplitude . Since the ... RBLOCK4 + was
observed to be a poor switch in all environments , as expected . Data for
RBPTTF4 + and ...

Molecular Wires and Nanoscale Conductors

Author:

Publisher:

ISBN:

Page: 416

View: 142

Molecular Electronics III

The success of digital optical data systems has stimulated widespread interest in
the search for photochromic systems as light - activated molecular memory
elements for data processing . 10 Switching chiral molecules with femtosecond
laser ...

Molecular Electronics III

Author: Jeffrey R. Reimers

Publisher:

ISBN:

Page: 332

View: 272

This volume explores various possibilities in the development of molecular electronics in its discussion of experiment, theory, design, fabrication, operating principles and applications of molecular-scale electronics.

Journal

( d ) Molecular Switches ; Feringa , B. L. , Ed .; Wiley - VCH : Weinheim , 2001 . ...
( b ) Balzani , V .; Credi , A .; Venturi , M. In Supramolecular Science : Where It is
and where It is Going ; Ungaro , R. , Dalcanale , E. , Eds .; Kluwer : Dordrecht ,
1999 ...

Journal

Author: American Chemical Society

Publisher:

ISBN:

Page:

View: 463

Transition Metals in Supramolecular Chemistry

The series will cover all areas from theoretical and modelling aspects through organic and inorganic chemistry and biochemistry to materials, solid-state and polymer sciences reflecting the many and varied applications of supramolecular ...

Transition Metals in Supramolecular Chemistry

Author: Jean-Pierre Sauvage

Publisher: John Wiley & Sons

ISBN: 0470511508

Page: 426

View: 683

Perspectives in Supramolecular Chemistry will relate recent developments and new exciting approaches in supramolecular chemistry. In supramolecular chemistry, our aim is to understand molecular chemistry beyond the covalent bond - the series will concentrate on goal-orientated supramolecular chemistry. Perspectives in Supramolecular Chemistry will reflect research which develops supramolecular structures with specific new properties, such as recognition, transport and simulation of biosystems or new materials. The series will cover all areas from theoretical and modelling aspects through organic and inorganic chemistry and biochemistry to materials, solid-state and polymer sciences reflecting the many and varied applications of supramolecular structures in modern chemistry. Transition Metals in Supramolecular Chemistry Edited by Jean-Pierre Sauvage, Université Louis Pasteur, Strasbourg, France The chemistry of weak forces and non-covalent interactions as pioneered by Pedersen, Lehn and Cram is considered to be the origin of modern supramolecular chemistry. 30 years ago transition metals and their complexes were not regarded as important to this science. Transition Metals in Supramolecular Chemistry clearly demonstrates that today, transition metal complexes are routinely used to build large multicomponent architectures which display new and exciting applications including molecular switches, liquid crystals, and molecular magnets. Contents * Ligand and Metal Control of Self-Assembly in Supramolecular Chemistry * Bistability in Iron (II) Spin-Crossover Systems: A Supramolecular Function * Luminescent Sensors with and for Transition Metals * The Chirality of Polynuclear Transition Metal Complexes * Design and Serendipity in the Synthesis of Polynuclear Compounds of the 3d-metals * Rotaxanes: From Random to Transition Metal-Templated Threading of Rings at the Molecular Level * Metallomesogens - Supramolecular Organisation of Metal Complexes in Fluid Phases * Self-Assembly of Interlocked Structures with Cucurbituril Metal Ions and Metal Complexes Reflecting contemporary science, Transition Metals in Supramolecular Chemistry will inspire scientists and students interested in coordination chemistry, magnetochemistry, molecular sensors and switches, liquid crystals and artificial systems.

Australasian Science

Rotaxane acts a chemical switch . It has two " stations " at which the molecular
shuttle can stop when an electron is added ( reduction ) . Chemical Switches A
number of synthetic molecules can also be made to behave in a reversible way ,
and ...

Australasian Science

Author:

Publisher:

ISBN:

Page:

View: 372

Molecular Nanoelectronics

Switches Molecular switches , unlike the previous components , are devices that
have no single bulk analog . A switch is a device that can be programmed to be
either highly resistive ( open ) or highly conductive ( closed ) . Molecular switches
 ...

Molecular Nanoelectronics

Author: Mark A. Reed

Publisher: Amer Scientific Pub

ISBN:

Page: 394

View: 327

And Perspective 225 -- Acknowledgments 225 -- R eferences 225 -- Chapter 9. NANOPARTICLES: BUILDING BLOCKS -- For Functional Nanostructures -- Corey Radloff, Cristin E. Moran, Joseph B. Jackson, Naomi J Halas -- 1. Introduction 229 -- 2. Building Blocks 230 -- 2.1. Nonmetallic Nanoparticles 230 -- 2.2. Semiconductor Nanocrystals 235 -- 2.3. M etal N anoparticles 241 -- 3. Assembly and Deposition Methods 244 -- 3.1. N anoshells 244 -- 3.2. Two- and Three-Dimensional Nanoparticle Assemblies 247 -- 3.3. Single-Particle Trapping and Manipulation 256 -- 4. A pplications 258 -- 4.1. Quantum Dot Corporation 258 -- 4.2. Nanospectra L.L.P 258 -- 4.3. SurroMed Incorporated 259 -- R eferences 259 -- Chapter 10. MOLECULAR- AND NANOCRYSTAL-BASED -- Photovoltaics -- Laura A. Swafford, Sandra J. Rosenthal -- 1. Introduction 263 -- 2. p-n Junction Silicon Solar Cells 264 -- 3. Photosynthesis: Nature's Solar Cell 266 -- 4. Molecular- and Nanomaterial-Based Photovoltaics 267 -- 4.1. Schottky Photodiodes 267 -- 4.2. Sandwich Heterojunction Photovoltaics 277 -- 4.3. Bulk Heterojunction Photovoltaics 279 -- 5. Future Photovoltaics 284 -- 6. Concluding Remarks 286 -- Appendix: Photovoltaic Efficiencies 286 -- A .1. Lighting Conditions 286 -- A.2. Calculating Photovoltaic Efficiencies 287 -- Acknowledgments 287 -- R eferences 287 -- Chapter 11. ORGANIC THIN FILM TRANSISTORS -- Hagen Klauk, Thomas N. Jackson -- 1. Introduction 291 -- 2. Pushing the Limits 296 -- 3. Device Architectures 297 -- 4. Flexible Substrate Technology 297 -- 5. Gate Dielectrics 299 -- 6. Low-Cost Proc.

CORDIS Focus

Nano'switch ' bridges biological and nano - worlds ' Frankly , some researchers
didn't think what we were doing was possible , ' says Dr Keith Firman , on the
completion ... However , we got our molecular switch to work , ' he told IST
Results .

CORDIS Focus

Author:

Publisher:

ISBN:

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View: 642