Contemporary Targeted Therapies in Rheumatology

Targeted therapies of rheumatic diseases have become a reality and have completely changed patient care as well as patient expectations.

Contemporary Targeted Therapies in Rheumatology

Author: Josef S. Smolen

Publisher: CRC Press

ISBN: 9780203694145

Page: 636

View: 947

Targeted therapies of rheumatic diseases have become a reality and have completely changed patient care as well as patient expectations. Initial success with therapies aimed at blocking TNF and IL-1 has stimulated the development of additional targeted approaches focused on other cytokines as well as specific cells and pathways involved in the path

Targeted Therapies in Rheumatology

This textbook serves as a comprehensive reference on the latest science underlying the development of biological therapies, as well as their use in animal and human studies of rheumatological disease.

Targeted Therapies in Rheumatology

Author: Josef S. Smolen

Publisher: Taylor & Francis

ISBN: 9781841841571

Page: 768

View: 804

This textbook serves as a comprehensive reference on the latest science underlying the development of biological therapies, as well as their use in animal and human studies of rheumatological disease. Part A covers targets of emerging therapies - targeting/manipulating cells, targeting cell surface receptors, targeting cytokines, inflammatory mediators and transcription factors, and targeting plasma molecules. Part B then examines the use and implementation of these new therapies in the clinic, covering their use in treating specific rheumatological conditions. Part C discusses issues relating to study design and regulatory issues in the US and Europe.

Targeted Treatment of the Rheumatic Diseases

Michael H. Weisman, Michael Weinblatt, James S Louie, and Ronald Van Vollenhoven offer their unique insights into choosing the correct pharmacological and non-pharmacological therapies for your patients.

Targeted Treatment of the Rheumatic Diseases

Author: Michael H. Weisman

Publisher: Elsevier Health Sciences

ISBN: 141609993X

Page: 471

View: 854

Michael H. Weisman, Michael Weinblatt, James S Louie, and Ronald Van Vollenhoven offer their unique insights into choosing the correct pharmacological and non-pharmacological therapies for your patients. Chapters cover the full breadth of rheumatic diseases, rheumatoid arthritis, lupus, connective tissue diseases, osteoporosis, regional pain disorders, and fibromyalgia. The full-color design presents detailed clinical photographs and treatment algorithms for visual guidance and easy reference. Covers the treatment of pediatric patients as well as adults so that you can properly address the particular needs of any patient you see. Features the guidance and specific recommendations of experts from United States and Europe for a state-of-the-art approach to the variety of treatments currently in use. Displays the clinical manifestations of rheumatic diseases in full color, along with treatment algorithms for easy at-a-glance reference.

Drugs Targeting B Cells in Autoimmune Diseases

This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome, ANCA-associated vasculitis and ...

Drugs Targeting B Cells in Autoimmune Diseases

Author: Xavier Bosch

Publisher: Springer Science & Business Media

ISBN: 3034807066

Page: 292

View: 260

This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome, ANCA-associated vasculitis and cryoglobulinemia. Organ-specific autoimmune diseases are discussed with respect to the use of B-cell directed therapies in neurological autoimmune diseases and autoimmune cytopenias. Situations in which B-cell targeted therapy may be indicated are identified, thereby offering comprehensive support for therapeutic decisions on the basis of the latest published evidence. The book also offers a valuable reference tool for rheumatologists, internists, nephrologists, immunologists, and all specialists involved in the multidisciplinary care of patients with rheumatic and systemic autoimmune diseases.

Cumulated Index Medicus

Lijec Vjesn 1998 May ; 120 ( 5 ) : 117-20 ( Eng . of patients with rheumatoid
arthritis after treatment with Springer Semin ... ( Hun ) The effects of recombinant
human erythropoietin on TNF - alpha - targeted therapy in rheumatoid arthritis (
New ...

Cumulated Index Medicus

Author:

Publisher:

ISBN:

Page:

View: 877

Skills in Rheumatology E Book

Vasc Health Risk Manag 2007;3(4):533–53. [56] Weisman MH, et al., 2010.
Management of acute thrombosis and secondary thrombosis prevention in APS.
Targeted treatment of the rheumatic diseases. 1st ed., Elsevier; Chapter 11. [57]
Snow ...

Skills in Rheumatology E Book

Author: Hani Almoallim

Publisher: Elsevier

ISBN: 0702074543

Page: 598

View: 351

This book is a quick aid for any clinician dealing with patients with rheumatic diseases. The major gap that we tried to fill by writing this book is the clinical relevance to practice! It is hardly ever seen that a resident in rheumatology is carrying any book about rheumatology in his/her rotation! Obviously, because there are no good books with relevance to the daily practice a resident is facing! Now, here are the specific objectives of the book. The chapters might be fulfilling more than one of these general objectives: To construct a clinical approach to patients with arthritis. To interpret laboratory findings in patients with rheumatic diseases. To prescribe and monitor drugs used to treat patients with rheumatic diseases. To construct a diagnostic approach to common medical problems in patients with rheumatic diseases. To provide an update in the classification and management of common rheumatic diseases based on international societies. The features and content in the book that will be most valuable: The first part which represent the basics in rheumatology practice. There will be a comprehensive chapter about how to approach history taking from patients presenting with a rheumatological problem. There will be also a simplified approach to MSK examination of common joints from a rheumatological perspective with the intention to diagnose arthritis and not to be mixed with sports injuries or other soft tissue problems. In the last section of the book, we will bring the latest classification criteria and the latest recommendation for management guidelines (they are so many!) in one section! We are not considering our book as a reference in how to manage patients with RA or SLE by prescribing appropriate drugs! We are going only to focus on the approach to the patients and providing the latest guidelines for management available for the reader of the book.

Rheumatology Highlights

In contrast , the optimal therapy would be one that could be administered for a
brief period while providing longterm benefits . The capacity of lymphocyte -
targeted therapies to ' switch off disease in animal models of autoimmunity has
been ...

Rheumatology Highlights

Author:

Publisher:

ISBN:

Page:

View: 489

The Journal of Rheumatology

951 Medicinal and Injection Therapies for Mechanical Neck Disorders : A
Cochrane Systematic Review P.M. Peloso , A.R. ... 1030 Meetings in
Rheumatology xii VOLUME 33 : SUPPLEMENT 78 MAY 2006 B Cell Targeted
Therapies : From ...

The Journal of Rheumatology

Author:

Publisher:

ISBN:

Page:

View: 898

Rheumatology

... product (such as a vnloadable or CD-ROM-based electronic version) should
online access to RHEUMATOLOGY web ... www.rheumtext.com In-depth
discussions on the hottest topics - including genetics and the latest targeted
therapies.

Rheumatology

Author: Marc C. Hochberg

Publisher:

ISBN:

Page: 2199

View: 137

The third edition of this publiction attempts to be the most comprehensive, authoritative rheumatology text, designed to meet the complete needs of all practicing and academic rheumatologists as well as all arthritis related health care professionals and scientists interested in disorders of the musculoskeletal system. The book is firmy grounded on modern medical science, integrating the relevant basic biology with current clinical practice.

Clinical and Experimental Rheumatology

Schematic representation of the proposed , highly complex interactions between
sex hormones , target cells and ... by gonadal hormones , sex hormone
replacement therapy has been introduced over the past 40 years for the
treatment of ...

Clinical and Experimental Rheumatology

Author:

Publisher:

ISBN:

Page:

View: 999

Arthritis

It may be that with fewer referrals to rheumatologists , there may be a greater
emphasis on the treatment of serious but ... sectors » Targeted therapies This is
undoubtedly the most exciting area of development in rheumatology today and
for ...

Arthritis

Author: Gabriel Stavros Panayi

Publisher:

ISBN:

Page: 208

View: 493

Providing information organized in a straightforward way, this series meets the needs of GPs, junior doctors, practice nurses and other primary care providers. It gives authoritative and accessible information, from clinical experts in the field, to assist with treatment decisions on arthritis.

Bulletin on the Rheumatic Diseases

Tunn and Bacon ( 7 ) have presented evidence for a benign and self - limited
course in early synovitis of RA patients . Because outcome predictors are
unavailable , we have limited ability to target therapy where it is needed most .

Bulletin on the Rheumatic Diseases

Author:

Publisher:

ISBN:

Page:

View: 634

Pharmacology

Mechanisms of action of DMARDs are reviewed by Bondeson (1997) and clinical
applications of antirheumatoid drugs are reviewed by Porter & Sturrock (1993).
Cytokine-targeted therapies for rheumatoid conditions are coming on line ...

Pharmacology

Author: H. P. Rang

Publisher:

ISBN: 9780443065743

Page: 839

View: 196

Adapted for the U.S., this New Edition of PHARMACOLOGY, a popular UK text, describes what drugs do and emphasizes the mechanisms by which they act. The U.S. edition is revised and updated to reflect the substantial differences in drug names, FDA approvals, terminology, and guidelines for use. It also boasts new and revised chapters to ensure that students are up to date on the very latest information. Each chapter begins with a summary of information essential to the chapter and key points are highlighted within the text to alert students to crucial concepts. Spanish version also available, ISBN: 84-8174-492-1

Textbook of Pediatric Rheumatology

... Although the initial excitement regarding biologic therapy was tempered by
either lack of efficacy or severe toxicity , more recent developments justify a great
deal of optimism for the development of new , more focused and targeted
therapies ...

Textbook of Pediatric Rheumatology

Author: James T. Cassidy

Publisher: Saunders

ISBN:

Page: 819

View: 574

Covering all essential information in a single volume, the Fourth Edition emphasizes the presentation, course of disease, treatment and prognosis of the major entities in the subspecialty of pediatric rheumatology. It is completely revised and updated. (Midwest).

Kelley s Textbook of Rheumatology

As mentioned , it is likely that celiac disease is an example of a Th1 disease , but
there is no experience with specific T cell - targeting therapy . BYPASS
ARTHRITIS - DERMATITIS SYNDROME Surgical treatment of overweight
patients by ...

Kelley s Textbook of Rheumatology

Author: Shaun Ruddy

Publisher:

ISBN:

Page: 1788

View: 342

Biologics for the Treatment of Rheumatoid Arthritis

This book provides a comprehensive overview of the available biologic therapies whilst comparing them to standard disease modifying anti-rheumatic drugs, and discusses how best to determine which therapy is most appropriate for an ...

Biologics for the Treatment of Rheumatoid Arthritis

Author: Ronald F van Vollenhoven

Publisher: Adis

ISBN: 9783319131078

Page: 132

View: 624

This book provides a comprehensive overview of the available biologic therapies whilst comparing them to standard disease modifying anti-rheumatic drugs, and discusses how best to determine which therapy is most appropriate for an individual patient in the framework of current guidelines. Biologics for the Treatment of Rheumatoid Arthritis is an up-to-date and concise practical guide to the latest therapeutic developments in this field. This book is an invaluable source of topical information for all rheumatologists and health care professionals treating patients with rheumatoid arthritis.

The Year Book of Medicine 2005

Edwards JC , Cambridge G : Sustained improvement in rheumatoid arthritis
following a protocol designed to deplete B lymphocytes . Rheumatology 40 : 205
- 211 , 2001 . Efficacy of B - Cell - Targeted Therapy With Rituximab in Patients
with ...

The Year Book of Medicine 2005

Author: Jamie S. Barkin

Publisher: Mosby Incorporated

ISBN: 9780323021098

Page: 627

View: 889

The Year Book of Medicine brings you abstracts of the articles that reported the year's breakthrough developments in medicine, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed! The 2004 topics include infectious diseases; hematology and oncology; the kidney, water and electrolytes; and the heart and cardiovascular disease and the digestive system. The Year Book of Medicine is published annually in September.